Live Bacterial Vectors—A Promising DNA Vaccine Delivery System
نویسندگان
چکیده
منابع مشابه
Live Bacterial Vectors-A Promising DNA Vaccine Delivery System.
Vaccination is one of the most successful immunology applications that has considerably improved human health. The DNA vaccine is a new vaccine being developed since the early 1990s. Although the DNA vaccine is promising, no human DNA vaccine has been approved to date. The main problem facing DNA vaccine efficacy is the lack of a DNA vaccine delivery system. Several studies explored this limita...
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Genetically attenuated microorganisms, pathogens, and some commensal bacteria can be engineered to deliver recombinant heterologous antigens to stimulate the host immune system, while still offering good levels of safety. A key feature of these live vectors is their capacity to stimulate mucosal as well as humoral and/or cellular systemic immunity. This enables the use of different forms of vac...
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ژورنال
عنوان ژورنال: Medical Sciences
سال: 2018
ISSN: 2076-3271
DOI: 10.3390/medsci6020027